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Cake day: June 13th, 2023

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  • An expanded genomic analysis of the dbSNP database revealed that this substitution was present in all but six of 650,058 human sequences, five of which were from individuals of Asian descent (Supplementary Fig. 1a). As the samples are deidentified, it is not possible to assess additional details about these individuals.

    Seems like we could learn a lot more about the effects of this substitution by finding and studying some of the modern humans who don’t have it, rather than by introducing it into mice.